JSI Tip 3808. How do I prevent the applications in the Registry RunOnce key from starting?

When a user logs on, the programs and documents in the run-once list are run just once, but never again. These entries are generally configured by installation routines.

To prevent the entries in the HKEY_LOCAL_MACHINESoftwareMicrosoftWindowsCurrentVersionRunOnce key and HKEY_CURRENT_USERSoftwareMicrosoftWindowsCurrentVersionRunOnce from starting, enable the Disable the run once list Group Policy at Computer ConfigurationAdministrative TemplatesSystem or User ConfigurationAdministrative TemplatesSystem.

If the policy is Not configured, you can implement it by setting the DisableLocalMachineRunOnce value name, a REG_DWORD data type, to 1, at HKEY_LOCAL_MACHINESOFTWAREMicrosoftWindowsCurrentVersionPoliciesExplorer or HKEY_CURRENT_USERSOFTWAREMicrosoftWindowsCurrentVersionPoliciesExplorer.