Should I use DFSR or SharePoint?

A. This question is very broad. Much depends on the data being stored and how it changes. DFSR is merely a replication technology; it can’t merge multiple changes to a file into one "complete version." If you have multiple locations, and you want the data available locally at those locations, and there's no danger of a data item replicating in two sites simultaneously (thereby causing a replication conflict), then DFSR is for you. If you require a more comprehensive check-in/check-out system to ensure data integrity so that only one person edits a file, then SharePoint is a better solution