SCVMM Management of Hyper-V in Different Domains

Q: Can a single System Center Virtual Machine Manager (SCVMM) instance manage Hyper-V servers in different domains?

A: Yes. SCVMM uses RunAs accounts to communicate to the Hyper-V hosts that it manages. If different security credentials are required that have administrative access for the hosts, then simply specify alternal RunAs accounts as the hosts are added to SCVMM for management.