Q: Can I perform a Live Migration from a Hyper-V host with an Intel processor to a Hyper-V host with an AMD processor in Windows Server 2012?

A: Live Migration allows a virtual machine (VM) to be moved from one Hyper-V host to another without any downtime to the guest OS. A processor compatibility feature allows a VM to be moved between Hyper-V hosts that have different versions of the same brand of processor, such that both servers have Intel or both have AMD-based processors. However, Live Migration even with processor compatibility enabled on the VM can't be used to move between a mix of AMD and Intel servers. Given how different AMD and Intel processors are, the ability to move a VM between servers running AMD and Intel is fairly unlikely.